Micronized progesterone is the natural female hormone progesterone formulated into very fine (“micronized”) particles so it can be absorbed better when taken. As an API (Active Pharmaceutical Ingredient), micronized progesterone is chemically identical to the progesterone made by a woman’s ovaries.

Medically, micronized progesterone is used in various hormone therapies. For example, in postmenopausal hormone replacement, it is given along with estrogen to prevent overgrowth of the uterine lining (endometrial hyperplasia) in women who still have a uterus. It is also prescribed to treat certain menstrual disorders; for instance, secondary amenorrhea (absence of menstrual periods) and other abnormal bleeding patterns. In fertility care, micronized progesterone is commonly used (often vaginally) to support the luteal phase and early pregnancy, though this use is beyond the basic label instructions.

Micronized progesterone is a prescription-only hormone medication. (In drugs.com terms, it’s essentially progesterone USP in a finely divided form, e.g. Prometrium® capsules contain 100–200 mg micronized progesterone. Because it is identical to natural progesterone, it generally has a side-effect profile similar to the body’s own hormone (e.g. it can cause drowsiness or breast tenderness, unlike some synthetic progestins).

Key Features & Top Health Benefits

• Ultra-Pure, Micronized API: Precision-milled micronized progesterone with superior solubility and bioavailability for optimal absorption, efficacy, and patient outcomes.
• Pharmaceutical Grade for Compounding: Meets USP (United States Pharmacopeia) standards for purity and potency—perfect for use in capsules, creams, suppositories, troches, and topical/dermal formulations.
• Supports Women’s Hormone Balance: Essential for menopausal hormone replacement therapy (HRT), perimenopause, and PMS symptom relief.
• Fertility and Reproductive Health: Widely used in fertility clinics and IVF protocols to support luteal phase, embryo implantation, and address luteal insufficiency.
• Compounding Pharmacy Essential: Preferred API for preparing custom hormone formulations (personalized dosing strengths and delivery forms) to optimize patient care and adherence.
• Bioidentical & Naturally Sourced: Matches the body’s own progesterone structure for fewer side effects and better tolerability than synthetic progestins or conventional HRT.
• Backed by Medisca Quality: Industry-leading standards—rigorously tested, batch-certified, and trusted by top healthcare and wellness providers worldwide.

Top Clinical & Wellness Applications

• Hormone Replacement Therapy (HRT) for Menopause / Perimenopause
• Fertility treatments and IVF cycles
• PCOS and menstrual cycle regulation
• PMS, PMDD, and symptom relief
• Endometrial support, premenstrual spotting
• Prevention of estrogen dominance
• Custom compounding: oral capsules, creams, gels, vaginal suppositories, troches, lozenges, rapid dissolve tablets

Why Choose Progesterone Micronized Powder by Medisca?

• High potency, purity, and reliability for safe patient outcomes
• Consistent particle size ensures even mixing in all dosage forms
• Versatile for every compounding application—pharmacy, clinic, wellness
• Batch-tested, cGMP and USP compliant for regulatory peace of mind
• Preferred by pharmacists, integrative MDs, OB/GYNs, and endocrinologists

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How to Use / Compounding Instructions

• For Licensed Compounding Professionals Only: Education, equipment, and facility must meet all regulatory and safety standards.
• Typical Applications: Capsule filling, cream and gel bases, vaginal or rectal suppositories, sublingual troches—all formulations to physician Rx specifications.
• Dosing: Recipe and strength per individualized prescription and clinical protocol.
• Storage: Store tightly sealed in a cool, dry place away from light and moisture; follow all USP and pharmacy grade handling protocols.

Possible Side Effects (Inform Patients)

Common:

• Mild drowsiness or dizziness
• Breast tenderness
• Bloating
• Spotting or change in menstrual pattern

Rare/Serious:

• Rash, abnormal vaginal bleeding, persistent headaches (seek provider guidance)

Compounded hormones should always be dispensed under medical supervision with ongoing professional monitoring; suitability and safety depend on patient’s health status, lab history, and prescribed regimen.

Precautions

• For Professional Compounding Use Only—Not for direct consumer use
• Prescription and handling must follow federal, state, and USP guidelines
• Consult prescriber for potential drug interactions, contraindications, and monitoring

Transform your custom hormone therapy offerings with Micronized Progesterone Powder For Compounding (API) —the global gold standard for bioidentical HRT, fertility, and personalized women’s health solutions. Trusted by pharmacists, specialists, and wellness providers everywhere.